Acetonitrile, an aliphatic nitrile, is widely used as an organic solvent and intermediate in organic syntheses. It is transparent to UV-visible light, which makes it highly applicable in spectrophotometric and fluorimetric techniques. MeCN is utilized as a mobile phase component in many chromatographic techniques, due to its low viscosity, high elution strength and miscibility in water. It also plays a major role as an extractant medium in liquid-liquid extraction, solid-phase extraction or microextraction.
Acetonitrile may be used as a solvent to prepare:
- 1,2-Azidoalcohols and 1,2-azidoamines via cerium(III) chloride assisted ring opening of epoxides and aziridines by sodium azide.
- Cyano-bearing indolinones by oxidative arylalkylation of olefins in the presence of palladium catalyst.
It may also be used as a reactant to synthesize:
- Bis (diphenylphosphino) acetonitrile by reacting with n-butyllithium and then with chlorodiphenylphosphine.
- β-Acetamido ketones via coupling reaction with ketones or ketoesters and aldehydes in the presence of cobalt(II) chloride.
1, 6×1, 2, 4×2 L in Sure/Seal™
100, 12×100 mL in Sure/Seal™
200 L in Pure-Pac™ 1
18 L in Pure-Pac™ 1
20, 50 L in Pure-Pac™ 2
|Methyl Cyanide, Cyanomethane, Ethanenitrile, Methanecarbonitrile, Ethyl Nitrile, Cyano, Acetonitril, Cyanure de Methyl, Methylkyanid, Mecn|